The Kite Runner by Khaled Hosseini - I read this back in middle school and it's one of the few books that really made me care about the main character. It deals with real situations and without spoiling it, what happens to Hassan is still one of the most shocking things I've read in any book. It's a very human book and I love it for those aspects which made me root for the characters.
1984 by George Orwell - I loved this look at a scary future of a false utopia in which people live under a false sense of security. Big Brother & The Thought Police brought fear into people. This book makes you wonder just how much we might be being monitored and how we might eventually lose our individualism. http://www.amazon.com/1984-60th-Anniversary-Plume-George-Orwell/dp/0452262933/ref=sr_1_1?s=books&ie=UTF8&qid=1367045839&sr=1-1&keywords=1984
The Catcher in the Rye by J.D. Salinger - Teenage angst, I could really relate to it when I read this book in high school. I felt like I could relate to Holden, not because I lost a sibling or anything, but I didn't want to lose my sense of youth. I always want to be young whenever I can be. I don't want to wake up in the morning and be a stern adult who doesn't know how to have fun anymore, I want to hold on to the innocence the most young people have.